RYUSENDO CO., LTD.
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History

1981
  • September
  • Established by Tsutomu Yae
1983
  • June
  • Launched “Neochlon G,” a spirulina tablet containing germanium (Patented for manufacturing in Japan, USA, UK, France and Switzerland)
1989
  • March
  • Launched “Vita-Onion,” onion extract tablets
1994
  • November
  • Launched “Ron Grape,” granulated ampelopsis extract powder
2004
  • February
  • Launched “Kabocha-Onion,” pumpkin and onion extract (OPtain®120) tablets
2006
  • May
  • Introduces water soluble Garcinia cambogia powder extract
  • June
  • Obtained the patent for OPtain120 in the U.S.
2007
  • February
  • Introduced undenatured type II collagen as a raw material
    Launched Kansetsu no tomo which contains undenatured type II collagen.
  • June
  • Introduced mixed berries extract. (OptiBerry®)
    Launched Bikenka® which contains OptiBerry.
  • December
  • Launched Nensho Shukan® which contains soluble Garcinia cambogia powder extract.
2009
  • November
  • Establishment of a production system for DetoSenna®.
    Launched DetoSlim®, which contains resistant dextrin, and DetoSenna®, a processed food.
2010
  • March
  • “Vita-Onion” patented
  • September
  • Introduced Ellagic acid (Iringia gabonensis extract)
2011
  • April
  • Yoshiaki Shiojima appointed president & CEO
2012
  • May
  • Head office moved to Nishi-ikebukuro, Tokyo
  • September
  • “OPtain120®” patented
    Introduced Wellmune® (Gluco-polysaccharide: β-1,3 / 1,6-glucan) in Japan
2013
  • August
  • ISO9001:2008 certification acquired
2014
  • April
  • Launched “Gluco-polysaccharide” which contains βglucan
  • May
  • NEXT-Ⅱ® (undenatured type Ⅱ collagen) obtained Self-Affirmed GRAS in the U.S.
  • August
  • Launched cosmetics, “immune one AQUAGEL”, which contains Yeast β-glucan
2015
  • May
  • NEXT-Ⅱ® (undenatured typeⅡ collagen) patented
  • September
  • Foods containing chicken cartilage extract, “Kansetsu no tomo®” has accepted by Consumer Affairs Agency as a Foods with Function Claims (Notification number: A95, functional ingredient: undenatured typeⅡ collagen).
2016
  • January
  • Launched “Kansetsu no Tomo” as a “Food with Functional Claims” supplement
2017
  • May
  • Introduced fingerroot extract (PandoraBeauty®)
  • October
  • Irvingia gabonensis extract containing food, “Body Challenge®” has accepted by Consumer Affairs Agency as a Foods with Function Claims (Notification number: C200, functional ingredient: ellagic acid derived from Irvingia gabonensis)
2018
  • January
  • Launched “Densetsu no Megami”, Fingerroot extract powder, Irvingia gabonensis extract powder, pineapple extract powder and Vitamin C capsules
  • February
  • Launched “Body Challenge” as “Food with Function Claims” supplement
  • September
  • Held the first academic seminar
  • October
  • NEXT-Ⅱ® (undenatured type Ⅱ collagen) patented in Canada
2019
  • September
  • Held the second academic seminar
2020
  • February
  • Establishment of a production system for Pyrroloquinoline quinone disodium salt (mnemoPQQ®)
  • April
  • Acquired the raw materials business and trademark rights in Japan, the U.S., EU and Korea for OptiBerry®
  • September
  • Held the third academic seminar
    “Bikenka®” which contains mangosteen extract has accepted by Consumer Affairs Agency as a Foods with Function Claims (notification number: F361, functional ingredient: Rhodanthenone B)
    “Body Challenge Z” which contains ellagic acid has accepted by Consumer Affairs Agency as a Food with Function Claims (notification number: F365, functional ingredient: ellagic acid)
  • October
  • “Body Challenge R” which contains ellagic acid has accepted by Consumer Affairs Agency as a Food with Function Claims (notification number: F425, functional ingredient: ellagic acid)
    “Body Challengeα” which contains ellagic acid has accepted by Consumer Affairs Agency as a Food with Function Claims (notification number: F426, functional ingredient: ellagic acid)
  • December
  • Launched “Bikenka®” and “Body Challenge Z” as “Food with Function Claims” supplements
2021
  • February
  • Launched “PQQ no Chikara”, Capsule of Pyrroloquinoline Quinone Disodium Salt
  • March
  • Launched “Densetu no Megami” as a “Food with Function Claims” supplements
  • June
  • Launched “immunoone AQUA GEL Kagayaki”, yeast β-glucan containing skin care gel.
  • September
  • The 40th anniversary
    Held the fourth academic seminar
2022
  • February
  • Establishment of production systems for product NEXT-Ⅱ® and sales
  • April
  • Launched “Body Challenge α” as a Foods with Function Claims supplements
    “Attaka Komachi” which contains ginger powder has accepted by Consumer Affairs Agency as a Food with Function Claims (notification number: G1268, functional ingredient: 6-gingerol, 6-shogaol)
  • May
  • Introduced “DygloFit®” from Gateway Health Alliance, Inc.
  • September
  • Held the 5th academic seminar
  • October
  • “Hizakoshi no tomo” which contains Undenatured typeⅡ collagen has accepted by Consumer Affairs Agency as a Food with Function Claims (notification number: H382, functional ingredient: undenatured typeⅡ collagen)
    “Kansetsu no tomo NEXT” which contains Undenatured typeⅡ collagen has accepted by Consumer Affairs Agency as a Food with Function Claims (notification number: H383, functional ingredient: undenatured typeⅡ collagen)
    “Kioku no tetsujin” which contains Pyrroloquinoline quinone disodium salt has accepted by Consumer Affairs Agency as a Food with Function Claims (notification number: H462, functional ingredient: pyrroloquinoline quinone disodium salt)
  • November
  • Launched “Attaka Komachi” as “Food with Function Claims”
  • February
  • Pyrroloquinoline quinone disodium salt (mnemo PQQ®) has obtained Self-Affirmed GRAS certification
2023
  • April
  • Started endowed course at the Faculty of Pharmaceutical Sciences at Teikyo University
    Launched “Kansetsu no tomo NEXT” as a Food with Function Claims
    Launched “Hizakoshi no tomo” as a Food with Function Claims
    Launched “Kioku no tetsujin” as a Food with Function Claims
  • May
  • Introduced “Rhodiolife®”(Rhodiola rose extract)
  • September
  • Held the 6th academic seminar
2024
  • September
  • Held the 7th academic seminar
2025
  • May
  • Introduced “ButiShield” (processed food with Calcium butyrate) Introduced “Bonlieve®” (olive leaf extract)
    Introduced “Slendacor®” (mixed herb extract)
  • June
  • NEXT-Ⅱ® (next generation undenatured type Ⅱ collagen) has obtained Halal certification
  • September
  • Held the 8th academic seminar
  • October
  • Introduced “Affron®” (saffron extract)
2026
  • January
  • Renewed company’s website
  • RYUSENDO CO., LTD.
  • 1-5-3 Nishi-ikebukuro,
    Toshima-ku, Tokyo 171-0021,
    Japan
  • TEL. 03-3985-8346
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